|
|
H+ + pyruvate + 2-oxobutyrate <=> (S)-2-hydroxy-2-ethyl-3-oxobutanoate + CO2
|
2.2.1.6
acetolactate synthase
|
–
|
|
BRENDA:
BS386670;
BS454179
KEGG:
R08648
MetaCyc:
ACETOOHBUTSYN-RXN
SABIO-RK:
6688
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
|
BRENDA:
BS453486
KEGG:
R05070
MetaCyc:
DIHYDROXYMETVALDEHYDRAT-RXN
|
|
|
|
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.67
2-aminohexanoate transaminase
|
–
–
|
|
BRENDA:
BS356522;
BS452227
KEGG:
R02199
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERILEU-RXN
SABIO-RK:
2171;
9086
|
|
|
|
2-aminobut-2-enoate <=> 2-iminobutanoate
|
3.5.99.7
1-aminocyclopropane-1-carboxylate deaminase
4.3.1.19
threonine ammonia-lyase
4.4.1.1
cystathionine gamma-lyase
4.4.1.2
homocysteine desulfhydrase
|
–
–
–
–
|
|
BRENDA:
BR50837
KEGG:
R11101
MetaCyc:
RXN-15121
|
|
|
|
2-iminobutanoate + H2O + H+ <=> 2-oxobutyrate + NH3
|
3.5.99.10
2-iminobutanoate/2-iminopropanoate deaminase
3.5.99.7
1-aminocyclopropane-1-carboxylate deaminase
4.3.1.19
threonine ammonia-lyase
4.4.1.1
cystathionine gamma-lyase
4.4.1.2
homocysteine desulfhydrase
|
–
–
–
–
–
|
|
BRENDA:
BR49538
KEGG:
R11098
MetaCyc:
RXN-15123
|
|
|
|
L-threonine <=> 2-aminobut-2-enoate + H2O + H+
|
4.3.1.19
threonine ammonia-lyase
|
–
|
|
BRENDA:
BR50836
MetaCyc:
RXN-15122
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate + NADP+ <=> H+ + (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
|
|
MetaCyc:
ACETOOHBUTREDUCTOISOM-RXN
|
|